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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

Eosinophil and Eosinophil Cationic Protein Level Raising in Dermatitis Due to Food Patients Umborowati, Menul Ayu; Sawitri, Sawitri; Hoetomo, Marsoedi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.225 KB) | DOI: 10.20473/bikkk.V27.2.2015.90-96

Abstract

Background: Food allergy prevalence worldwide has been increase. Skin is secondary most often target organ in food allergy reaction. Food allergy affects 35% atopic dermatitis (AD) patients. Diagnosis of food allergy  is still challenge because signs are not specific. Previous researches showed eosinophil and eosinophil cationic protein (ECP) role in food allergy reaction on gastrointestinal tract, but none on dermatitis due to food. Purpose: To evaluate eosinophil and serum ECP in dermatitis due to food. Method: This is a descriptive observational cross sectional study, with dermatitis due to food patients in Dermatovenereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya as subjects. Subjects has been collected trough consecutive sampling during 3 months, then data were analysized descriptively Results: Serum ECP level of dermatitis due to food patients were above normal range in all subjects, with mean level 108.5 µg/L, lowest level 33.011 µg/L and higher level 284.849 µg/L. Mean eosinophil of dermatitis due to food patients just arise above normal limit (0.413µg/L). AD patients were 48.4% among all subjects. Mean serum ECP level of AD patients was higher (121.703 µg/L) than non-AD (96.123 µg/L). Conclusions: Eosinophil and ECP seems have role in dermatitis due to food pathogenesis. Serum ECP examination can be benefits to monitor dermatitis due to food severity.Key words: dermatitis due to food, eosinophil, serum eosinophil cationic protein.
The Profile of Erysipelas and Cellulitis Patients Novarina, Ryski Meilia; Sawitri, Sawitri
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.74 KB) | DOI: 10.20473/bikkk.V27.1.2015.32-40

Abstract

Background: Erysipelas and cellulitis are acute infectious serious skin diseases, due to the entry of bacteria through the unintact skin barrier and can be fatal. Purpose: To determine the clinical manifestation and management of hospitalized erysipelas and cellulitis patients at the dermatolovenerology inpatient Dr. Soetomo General Hospital in period of 2008-2011. Methods: The study was conducted retrospectively based on the medical records of the hospitalized patients include case number, gender, age, main complaint and duration, trigger factors, concomitant factors that can be as the underlying disease, lesion site, laboratory examinations, treatments, length of treatment associated with Erythrocyte Sedimentation Rate (ESR) and the prognosis. Results: The erysipelas and cellulitis cases were 65 cases (1.9%) of the total hospitalized cases of skin diseases, with the number of men and women were 36 and 29 patient, respectively. The highest age group were 45-65 years (35.4%). Main complaint was swelling, redness and pain (66,2%) and the duration of complaints 1-7 days (81.5%), Most triggering factors due to scratching (34%). Anemia (30,8%) is the most underlying disease. The majority of lesion sites are in the lower extremities in 56 patients (86.1%). Laboratory tests showed anemic (30.8%), leukocytosis (44.6%) and (76.9%) ESR > 20mm/h (76.9%). The specimen of the lesion of 18 cases were cultured, there were found majority bacterial were Staphylococcus aureus (37.5%). The managements of treatment of 25 cases (38.5%) were consisted: immobilization, intravenous injection of Ampicillin and wet dressing with normal saline, 15 cases with ESR>50mm/h were treated for 8 -14days. The complications (gangrenosum cellulitis) were found in 1 case (1,5%), and 40 patients (61.5%) discharge from hospital in a recovery state. Conclusion: The management of patients with erysipelas and cellulitis had been appropriate based on the diagnosis and treatment guidelines. Staphylococcus aureus is the most frequent bacteria found in culture.Key words: erysipelas, cellulitis, Staphylococcus aureus.
Profile of Scabies in Children Paramita, Kartika; Sawitri, Sawitri
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.621 KB) | DOI: 10.20473/bikkk.V27.1.2015.41-47

Abstract

Background: Scabies is a common parasitic infestation of the skin caused by Sarcoptes scabiei. Scabies is a common public health problem that occurs throughout the world with an estimated prevalence of 300 million individuals. Factors that lead to the high prevalence of scabies include high humidity, lack of sanitation, overcrowding, malnutrition, poor personal hygiene, knowledge, attitude, and behaviour of less supportive healthy lifestyle. Although scabies is not fatal or life-threatening, but the disease can be severe and persistent, which may lead to weakness and secondary skin infections. Purpose: To evaluate the clinical presentation, diagnosis, and treatment of scabies in children at Dermatovenereology outpatient clinic of Dr. Soetomo General Hospital Surabaya. Methods: A retrospective study within 2009 to 2011 using medical record of new patients, aged < 14 years old. Results: The total patients of scabies were 282 patients (5,9% of all pediatric patients in outpatient clinic). Most common group of age was 5-14 years old with the total 180 patients (63,8%), the majority of complaint was itching at night (90,1%), the most frequent location of the lesions was in the web of the fingers and the most common source of transmission is the patients family  (51,4%). The most given topical scabisid was Permethrin cream 5% (97,3%). Conclusions: The diagnosis of scabies could be established by anamnesis and physical examination. Patients education is needed to reduce the reinfection and cut the source of transmission.Key words: scabies, children, Sarcoptes scabiei, retrospective study.
Oral Corticosteroid Therapy in Leprosys new patients with Type 2 Reaction Listiyawati, Irma Tarida; Sawitri, Sawitri; Agusni, Indropo; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (134.721 KB) | DOI: 10.20473/bikkk.V27.1.2015.48-54

Abstract

Background: Leprosy type 2 reactions is an acute inflammatory episode in lepromatous leprosy patient that ascociated with deposition of immune complexes. Standard regiment for severe reaction is corticosteroid. Almost Leprosy type 2 reactions patients become chronic and recurrent so it implicates to more complications if it was not managed well. Purpose: To determine the distribution of type 2 reactions patients which treated with oral corticosteroid in leprosy division of dermatovenereology outpatient clinic of Dr. Soetomo General Hospital. Methods: Retrospective study using new patients medical record during the period of January 1 2009 until December 31 2013 and the observation continued until December 31 2013. Results: The total type 2 reactions patients with oral corticosteroid was 112 patients, mostly were male aged between 25-64 years and has the Lepromatous Leprosy (LL) type (33%), the reactions happened after RFT  (43.8%), 65.2% had metil prednisolon medication, the initial equivalent dose was 30 mg in 32.1% patient. 21.4% patient had more than one cycle  of corticosteroid therapy and 8.9% patient had the steroid side effect. Conclusion: Leprosys type 2 reactions tend to be chronic and recurrent and the impact were patients got longterm continuously corticosteroid medication, so the patients need to be monitored including side effects.Key words: leprosys type 2 reaction, oral corticosteroid, side effects.
Perbedaan Dermatitis Seboroik dan Psoriasis Vulgaris Berdasarkan Manifestasi Klinis dan Histopatologi Astindari, Astindari; Sawitri, Sawitri; Sandhika, Willy
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.04 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-7

Abstract

Latar belakang: Dermatitis seboroik (DS) dan psoriasis sering sulit dibedakan baik secara klinis maupun secara histopatologi. Anamnesis yang tepat dengan memperhatikan usia, riwayat keluarga, dan pemeriksaan klinis yang teliti serta ditunjang dengan pemeriksaan histopatologi, dapat menentukan diagnosis yang tepat. Tujuan: Mengevaluasi perbedaan DS dan psoriasis supaya klinisi dan patolog bisa membuat diagnosis yang benar.Telaah kepustakaan: Secara epidemiologi, terdapat berbagai perbedaan antara DS dan psoriasis. Hal itu bisa dilihat dari usia saat timbulnya lesi, jenis kelamin, ras, maupun genetik. Lokasi lesi dan manifestasi klinis juga mempunyai ciri yang berbeda. Biopsi kulit dibutuhkan untuk membantu menegakkan diagnosis yang tepat.Gambaran histopatologi DS bervariasi sesuai dengan perjalanan penyakitnya: akut, sub-akut, dan kronis, sedangkan psoriasis mempunyai ciri khas berupa pemanjangan rete ridges, abses Munro atau adanya abses Kojog. Simpulan: Terdapat beberapa perbedaan antara DS dan psoriasis dari usia pertama kali muncul lesi, lokasi lesi, manifestasi klinis dan gambaran histopatologi.Kata kunci: dermatitis seboroik, psoriasis, manifestasi klinis, gambaran histopatologi.